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 Vol. 14 No. 1, July 2005
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AAP Grand Rounds 14:8-9 (2005)
© 2005 American Academy of Pediatrics

ENVIRONMENTAL HEALTH

Arsenic Reduces Children’s Intellectual Function

Source: Wasserman GA, Liu X, Parvez F, et al. Water arsenic exposure and children’s intellectual function in Araihazar, Bangladesh. Environ Health Perspect. 2004;112:1329–1333. Erratum in: Environ Health Perspect. 2004;112:A980.[Medline]

The first 20% of the full text of this article appears below.

Arsenic (As) has long been recognized to cause adverse neurologic outcomes among adults with chronic occupational exposures, but little information exists on its toxic effects in children. The authors from Columbia University, New York and Bangladesh investigated intellectual function in 201 children 10 years of age residing in Araihazar, Bangladesh. Bangladesh has been a focus of concern about As exposure because tube wells, drilled to provide sanitary water, have delivered drinking water with elevated levels of arsenic. This report is part of a longitudinal study of the environmental risks to people in Araihazar, in which 11,749 adults had been enrolled. Four hundred of these adults’ children, aged 9.5 to 10.5 years, were randomly selected to participate in the pediatric study. The 201 children (98 male) ultimately participating in the study were asked to undergo medical examinations including measurement of growth, provision of urine specimens for As and its metabolites, and venous blood sample for measurement of lead (Pb) and hemoglobin concentrations. There were many reasons patients did . . . [Full Text of this Article]

Lynn R. Goldman, MD, MPH, FAAP
Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD